Retatrutide research peptide

Retatrutide peptide, also known by the code LY3437943, is a synthetic 39 amino acid peptide supplied here as lyophilized powder for laboratory research. It is a single molecule that activates three receptors involved in energy balance, which has made it one of the most discussed compounds in current metabolic research.

What is Retatrutide peptide?

Retatrutide is an agonist at the glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide-1 (GLP-1) and glucagon receptors. A C20 fatty diacid side chain lets the molecule bind albumin, which extends its half-life. Because Retatrutide peptide engages all three receptors at once, it is often described as a triple agonist.

It was developed as an investigational compound and has been the subject of large clinical trial programmes. The material listed here is a laboratory reference compound and is not a medicine. A general overview is available in the retatrutide reference article.

Retatrutide peptide research areas

In the published literature, Retatrutide peptide has been examined in the following areas, mostly in cell and animal models:

• Incretin and glucagon receptor pharmacology
• Energy expenditure and body weight regulation models
• Glucose homeostasis
• Hepatic lipid metabolism

This summary is provided for context only. It is not a statement of use, safety or efficacy.

Retatrutide peptide specifications

• Sequence: 39 amino acid modified peptide with a C20 fatty diacid side chain
• Molecular formula: C₂₂₁H₃₄₂N₄₆O₆₈
• Molecular weight: 4731.3 g/mol
• CAS number: 2381089-83-2
• Length: 39 residues
• Form: lyophilized (freeze-dried) powder in a sealed vial

Buy Retatrutide peptide for research

We supply Retatrutide peptide in research grade 5 mg and 10 mg vials. Current prices are listed in the table further down this page. Use the Order button beside any size to send an enquiry with that item already filled in.

Each lot of Retatrutide is analysed for purity by HPLC and for identity by mass spectrometry, and a Certificate of Analysis is supplied with the order. If you need a document for a specific lot before you buy, ask through the contact page.

Wholesale Retatrutide peptide orders

Wholesale orders start at a minimum of 50 units, and you can request any quantity above that. Tell us the size and number of vials you need and we will confirm the total by email. We accept Apple Pay, Zelle, Chime, Cash App, USDT and Bitcoin.

How to store Retatrutide peptide

Keep the lyophilized powder at -20°C, protected from light and moisture, for long-term storage. After reconstitution, store the solution at 2 to 8°C and use it within the timeframe shown on the Certificate of Analysis. Avoid repeated freeze and thaw cycles, which can degrade any peptide.

Researchers who work with Retatrutide often also order SS-31 peptide. You can see every compound we carry in the research peptide catalogue.

Retatrutide peptide: common questions

What purity is your Retatrutide peptide?

Purity is measured by HPLC for every lot and printed on the Certificate of Analysis that ships with it. Identity is confirmed separately by mass spectrometry, so you can check both what the material is and how pure it is before you use it.

Why is Retatrutide peptide supplied as a powder?

Peptides are far more stable dry than in solution. Freeze-drying removes water without heat, which protects the peptide during shipping and storage. The powder is reconstituted in the laboratory shortly before it is needed.

Can I order a single vial?

Our standard terms are wholesale, with a minimum order of 50 units. If you need a smaller quantity for evaluation, send an enquiry and tell us what you are looking for.

Is Retatrutide peptide for human use?

No. It is sold for laboratory and in-vitro research use only. It is not for human or animal consumption and is not intended to diagnose, treat, cure or prevent any disease.